Search Results

VSV/NDV HYBRID VIRUS CANCER THERAPY

Sep 16, 2018

| Reference: 

B75267

  • ‍VSV/NDV hybrid enables efficient tumor cell killing.
  • VSV/NDV hybrid virus effectively overcomes the safety concerns of each parental virus and combines the advantages of both vesicular stomatitis virus (VSV) and Newcastle disease virus (NDV) vectors
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HYDROGELS: INJECTABLE DEPOT-SYSTEMS

Sep 16, 2017

| Reference: 

B76151

  • ‍novel hydrogels for therapeutic applications that gelatinize by a dual mechanism based on Diels-Alder reaction and physical crosslinking
  • stability and stiffness can be adjusted to therapeutic need
  • hydrogels are stable, in situ forming, non-toxic and particularly suitable for controlled drug release
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PROTEIN PURIFICATION/IMMOBILIZATION THROUGH NEG-PEPS

Sep 16, 2017

| Reference: 

B76080

  • negPeps (magnetic particle binding peptides) are novel peptides with the potential to replace the common affinity tags based protein purification/immobilization 
  • negPeps bind to magnetic nanoparticles in a reversible and controlled manner
  • no specific surface functionalization necessary 
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COMPRESSED AIR STORAGE FOR INDUSTRIAL APPLICATIONS

Sep 16, 2017

| Reference: 

B76054

  • ‍Energy and money savings 
  • Efficient gas storage (e.g. hydrogen) Improved availability
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CONCEPT FOR HERMETIC, LOW HEAT, MINIMUM INDUCTION PACKAGING

Sep 16, 2017

| Reference: 

B76018

  • ‍Power electronic packaging with dust protection 
  • Optimized thermo management 
  • Minimization of parasitic inductances
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MODIFIED BNC FOR CHIP CARDS AND MEDICINE

Sep 16, 2017

| Reference: 

B76007

  • novel chip technology that can be used as a data storage system, as a computer chip or a wearable
  • Principle: modification of bacterial nanocellulose (BNC) with light-gated DNA-Polymerases and other components 
  • Enables information read in and read out by using DNA, Polymerases and Exonucleases
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NEW PROCESS FOR HIGH PERFORMANCE POLYMERS

Sep 16, 2017

| Reference: 

B75246

  • ‍synthesis of known polymers to be simpler and more cost-effective 
  • conversion of monomers which until now have not yet been polymerized by conventional methods 
  • highly active catalyst
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LALISTAT: TREATING MYCOBACTERIAL DISEASES

Sep 16, 2017

| Reference: 

B75235

  • ‍novel approach for treating tuberculosis (TB) by the Lipase inhibitor Lalistat
  • Lalistat specifically abrogates the intracellular growth of mycobacterium tuberculosis
  • The use of Lalistat in combination with known antimycobacterial might offer an urgently needed opportunity to improve and shorten TB therapy
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QUICK SIMULATION OF THE LOAD ON A DISTRIBUTION GRID

Sep 16, 2017

| Reference: 

B75231

  • ‍Electrical distribution grid simulation
  • Extremely small computational time 
  • Versatile implementiation (large and small grids)
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RAPID FOCUS DETERMINATION DURING LASER BEAM WELDING

Sep 16, 2017

| Reference: 

B75226

  • ‍Rapid focus determination 
  • Upgradeable Easy calibration of scanner optics
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INTERACTIVE ROBOT SURFACE

Sep 16, 2017

| Reference: 

B75182

  • ‍Intuitive Human Robot Interaction 
  • Context-based communication 
  • Robot-robot recognition
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FRAME SKIPPING ULTRA LOW DELAY VIDEO TRANSMISSION SYSTEM

Sep 16, 2017

| Reference: 

B75157

  • ‍Ultra-low video transmission 
  • Extremely low latency 
  • Remote Controlling
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NEW THERMALLY STABLE EXPLOSIVE

Sep 16, 2017

| Reference: 

B75154

Highlights and advantages of TKX-55 compared to commercially available and widely used explosives, e.g. PYX and HNS:

  • thermally stable, up to 335 °C
  • high performance, showing high density (1.837 g.cm-3 ) and high velocity of detonation (8030 m.s-1)
  • yielding detonation pressure over 270 kbar  and low sensitivity
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LIGHT SENSOR FOR FAR INFRARED (4-30 μm)

Sep 16, 2017

| Reference: 

B75131

  • ‍Detector design based on resonance tunneling diode 
  • Range 4-20 μm, high sensitivity, high speed
  • Ideal replacement for toxic HgCdTe-Detectors
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SnIP: A NEW SEMICONDUCTOR

Sep 16, 2017

| Reference: 

B75074

  • ‍Tin phosphor iodide (SnIP) is a new semiconductor material
  • Photoluminescence in the visible makes it interesting for solar cells and light emitting diodes
  • First inorganic double helix structure material
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MONOLITHICALLY INTEGRATED NANOWIRE LASERS - III-V-LASERS ON SILICON

Sep 16, 2017

| Reference: 

B75073

  • ‍Monolithically integrated nanowire laser
  • Cmos conform integration of telecom lasers into silicon chips
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INTUITIVE PROGRAMMING OF ROBOT SYSTEMS

Sep 16, 2017

| Reference: 

B75045

  • ‍Intuitive programming of robot components 
  • Optimisation of the temporal synchronisation 
  • Fast instruction phase of the workers
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CANNULA FOR OCULAR MICRO-INJECTION

Sep 16, 2017

| Reference: 

B75028

  • ‍Intra- and sub-retinal targeted administration of drugs 
  • Easy and highly precise targeting 
  • Treatment of Age-related Macular Degeneration (AMD)
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SOOT REDUCTION DEVICE FOR GASIFICATION OF COMBUSTIBLES

Sep 16, 2017

| Reference: 

B75024 / B76027

  • ‍Renewable energy 
  • Biomass combustion 
  • Reduction of particulate matter
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COMPUTER VISION AND PATTERN RECOGNITION TASKS VIA PLAYSOURCING

Sep 16, 2017

| Reference: 

B75007

  • ‍Playsourcing and Crowdsourcing 
  • Tumor Segmentation 
  •  Processing of Histology and Image Data
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3D-PRINTING USING FOCUSED SUPER SONIC BEAMS

Sep 16, 2017

| Reference: 

B75001

  • ‍Ultra sonic 3d printing allows manufacturing from the volume
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PROCESSING A FOAM WORK PIECE

Sep 16, 2017

| Reference: 

B74222

  • ‍New product properties 
  • Better processing Flexible processing
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WET-LAID MEETS ELECTROSPINNING

Sep 16, 2017

| Reference: 

B74211

  • milder to skin compared to sodium dodecyl sulfate (SDS), in combination with a reduced sensitivity to water hardness
  • low production costs compared to ethoxylated anionic surfactants
  • enhanced washing ability and solubilizing power due to high water solubility
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NEW DRUG TARGET IN ALZHEIMER DISEASE

Sep 16, 2017

| Reference: 

B74174

  • Aη-α as a new drug target and / or diagnostic marker for Alzheimer disease
  • Presence of Aη-α fragments in AD brains should be taken into account for development/applicati- on of drugs targeting Aβ or inhibiting β-secretase, since these lead to accumulation of Aη-α
  • Antibodies to detect η-secretase pathway peptides are available
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A SYSTEM FOR HARVESTING ELECTRICAL ENERGY DURING SKI TOURING

Sep 16, 2017

| Reference: 

B74129

  • ‍Energy harvesting Ski touring 
  • Continual recharging of energy reservoirs
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ONE-POT PROCEDURE FOR NCC ISOLATION

Sep 16, 2017

| Reference: 

B74068

  • ‍Conventional Production of NCC is complex, expensive and takes several days
  • Novel simplified method for NCC isolation: neutralization-based isolation
  • significantly enhanced yield, accelerated process and reduced water usage
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A NEW TARGET IN CANCER THERAPY

Sep 16, 2017

| Reference: 

B74064

  • ‍cancer cells use an extracellular citrate supply as an important energy source and substrate for the synthesis of critical cellular building blocks (e.g. fatty acids). 
  • a highly specialized plasma membrane protein (pmCiC, plasma membrane citrate carrier) was found to be responsible for citrate uptake in cancer cells
  • pmCiC is a novel and specific marker and therapeutic target for cancer cells
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INDEXING OF HEMODYNAMIC PARAMETERS CONSIDERING THE INDIVIDUAL CONTEXT

Sep 16, 2017

| Reference: 

B74058

  • ‍Better assessment of patient health status and an easily accesible presentation
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METHOD AND DEVICE FOR 2D-SEPARATION OF IONIC SPECIES

Sep 16, 2017

| Reference: 

B74051

  • ‍Efficient separation of bioanalytical samples 
  • High troughput High sensitivity
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HYDRODABCYL: A HYDROPHILIC DARK QUENCHER

Sep 16, 2017

| Reference: 

B74047

  • ‍Hydrodabcyl: A hydrophilic alternative to the commonly used dark quencher Dabcyl
  • Non-immunogenic and non-toxic
  • Perfectly suitable for a large variety of biological and biochemical systems
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GPC3-SPECIFIC TCR FOR IMMUNOTHERAPY OF HCC

Sep 16, 2017

| Reference: 

B74044

  • discovery of so far unknown immunodominant GPC3-epitopes and the according T cell receptor (TCR)
  • tumor-associated antigen Glypican-3 (GPC3) is highly suitable for an immunotherapeutic approach
  • offers new opportunities for the detection, diagnosis, prognosis, prevention and/or treatment of liver cancer, in particular HCC, or other tumors expressing GPC3 
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METHOD FOR DEMODULATION AND DEMODULATOR

Sep 16, 2017

| Reference: 

B74021

  • ‍Low energy solution for 5G-standard telecommunication
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SMALL MOLECULE HDAC6 INHIBITORS

Sep 16, 2017

| Reference: 

B73271

  • ‍HDAC6 is a promising target for the treatment of chronic immune and inflammatory disorders such as rheumatoid arthritis (RA)
  • Marbostat are new small molecule inhibitors of HDAC6 with superior characteristics: in comparison to the established HDAC6 inhibitor Tubastatin A, the new inhibitors are more potent and specific, and most importantly they highly and selectively inhibit the enzyme activity of HDAC6 without destroying the protein.
  • Provision of a viable alternative to first line NSAIDs (non-steroidal anti-inflammatory drugs) in the treatment of RA
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IMPROVING STABILITY AND SECRETION OF ANTIBODIES

Sep 16, 2017

| Reference: 

B73076

  • Improvement of the biophysical properties of antibodies and enhancement of antibody secretion by imitating the stabilizing structural elements of shark antibodies
  • CL domain is modified by a conservative exchange of amino acids at two positions
  • Compared to the wild type CL, the melting point of the modified CL domain is almost 10°C higher and its stability against urea-induced denaturation is also markedly increased 
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FAST AND EXACT CALCULATION OF THE EFFICIENCY OF COMBUSTION PROCESSES

Sep 16, 2017

| Reference: 

B72156

  • ‍Precise specifications of turbines and engines 
  • Accurate calculation of efficiencies 
  • Guaranteed performance
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NEW SEROTONIN RECEPTOR AGONISTS

Sep 16, 2017

| Reference: 

B72118

  • ‍new serotonin receptor 5HT1P agonists (5-Benzyloxyindalpine, 5 BOIP) for the treatment or prevention of GI diseases such as constipation and functional dyspepsia and, in particular, for relieving GI symptoms
  • In the proximal stomach, 5BOIP evokes muscle relaxation, thereby improving the gastric accommodation reflex
  • 5 BOIP is highly specific, extremely stable against hydrolysis and oxidation and is much more convenient in production than other known agonists
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SMALL MOLECULE INHIBITORS OF CD40-TRAF6 INTERACTIONS

Sep 16, 2017

| Reference: 

B72031

  • ‍new selective inhibitors for treatment of chronic inflammatory diseases, such as atherosclerosis, obesity and multiple sclerosis
  • inhibitors selectively block CD40-TRAF6 interactions
  • The selective blockage of the CD40-TRAF6 interactions strongly reduces inflammation, whereas unwanted immune-suppressive side effects are reduced
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METHOD FOR IDENTIFICATION OF TARGET ANTIGENS OF T-CELLS

Sep 16, 2017

| Reference: 

B70007

  • ‍Identify peptide antigens of any CD8 restricted TCR (CD4 ongoing)
  • Affinity independent and extremely sensitive method
  • Focused on autoimmune diseases and psoriasis but also applicable to tumor immunology
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CHOLINE COMPOUNDS AND THEIR USE AS SURFACTANTS

Sep 16, 2017

| Reference: 

B69024

  • milder to skin compared to sodium dodecyl sulfate (SDS), in combination with a reduced sensitivity to water hardness
  • low production costs compared to ethoxylated anionic surfactants
  • enhanced washing ability and solubilizing power due to high water solubility
Read more