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• The use of DAT for immunotherapies

  B84103

  The use of DAT for immunotherapies

• Antidromic strategies to target RASopathies

  B82137

  Antidromic strategies to target RASopathies

  • RAS detected at low levels on cell surface independent of the HLA complex
  • Targeting of extracellularly expressed RAS on cancer cells via bispecific T cell engager
  • Relevant for novel immunotherapies for RAS-driven malignancies
• NF-κB-activated dendritic cells

  B71259

  NF-κB-activated dendritic cells

  • that has very little adverse effects and overcomes the limitations of DC based immunotherapy approaches
  • DCs activation is mediated by via mRNA transfection
  • Activated DCs lead to strong expansion of memory T cells and are much more stable than other DC vaccination products

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