Superior BChE inhibitors for Alzheimer’s Disease
Superior BChE inhibitors for Alzheimer’s Disease
- Highly potent BChE inhibitors
- BChE inhibitors with neuroprotectant properties
- Long and controllable duration of action
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Superior BChE inhibitors for Alzheimer’s Disease
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Amyloid Inhibitory Peptides for Alzheimer’s Disease and Diabetes
Amyloid Inhibitory Peptides for Alzheimer’s Disease and Diabetes
- macrocyclic peptides (MCIPs): novel class of nanomolar amyloid inhibitors of both Aβ40(42) and IAPP or of Aβ40(42) alone
- candidates/leads for macrocyclic peptide‐based anti‐amyloid drugs
- scaffolds for the design of small‐molecule peptidomimetics for targeting amyloidogenesis
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New drug target in Alzheimer’s disease
New drug target in Alzheimer’s disease
- Aη-α as a new drug target and / or diagnostic marker for Alzheimer’s disease
- Inhibition of β-secretase leads to accumulation of Aη-α
- Antibodies to detect η-secretase pathway peptides are available
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