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• Cytosolic RNA depletion by polymeric nanoparticles

  B83117

  Cytosolic RNA depletion by polymeric nanoparticles

  • Mucin nanoparticles cross-linked with anti-miRNA oligonucleotides
  • Treating systemic diseases associated with increased cellular RNA levels
  • Depletion of miRNA-21 reduced tumor growth in vivo by 50%
• Advanced Radio-guided Surgery using Nanoparticles: Radiopharmaceutical for the Detection of Sentinel Lymph Nodes

  B82027

  Advanced Radio-guided Surgery using Nanoparticles: Radiopharmaceutical for the Detection of Sentinel Lymph Nodes

  • Radio-guided Surgery
  • Radiopharmaceutical
  • Nanotechnology
• The T-Cell-Therapy Success Code: Signatures of recent T-cell activation allow isolation of highly functional tumor-specific T cell receptors

  B81078

  The T-Cell-Therapy Success Code: Signatures of recent T-cell activation allow isolation of highly functional tumor-specific T cell receptors

  • Cost-effective isolation of highly functional tumor-specific TCRs
  • Method using predictive markers to identify TCRs of high functional quality
  • Isolation of TCRs from easily accessible peripheral blood
• New cell therapy cures metastatic cancer in mouse

  B81137

  New cell therapy cures metastatic cancer in mouse

  • New RESURRECT NK and T cell therapy cures metastatic cancer in mouse
  • RESURRECT T and NK cells overcome immunosuppression in tumors and metastases
  • RESURRECT cells are effective in tumors resistant to standard immunotherapies
• Anti-PSMA antibodies for therapeutic and diagnostic purposes

  B80048

  Anti-PSMA antibodies for therapeutic and diagnostic purposes

  • Anti-PSMA antibody with sub-nanomolar affinity high specificity for native PSMA and good thermal stability
  • Pre-clinical optimization for developability
  • Among others, suitable for antibody-drug-conjugates, photodynamic therapy or imaging
• Liposome-encapsidated bioactive hexapeptides for targeted pancreatic cancer therap

  B80078

  Liposome-encapsidated bioactive hexapeptides for targeted pancreatic cancer therap

  • Targeted tumor therapy for highly aggressive pancreatic cancers
  • Particularly suited for combinational therapy
  • Targeted therapies for human solid tumors bearing wild-type TP53

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