Search Results

EFFICIENT CONDENSATION FOR ORGANIC RANKINE CYCLES

Nov 7, 2018

| Reference: 

B76094

  • Higher electricity output and cheaper production costs/larger profit margin
  • Market: For industrial waste heat in Germany: 65 PJ/a (T>150°C)
  • The invention can be adapted in novel products by manufacturers or as a retrofit in existing plants
Read more

INFINITE LOOP DETECTION

Nov 7, 2018

| Reference: 

B76069

  • Hardware or software implemented infinity loop detection,
  • Efficient way to identify suspicious branch sequences on-the-fly
  • Improves software savety and security
Read more

SPEEDING UP COMBINED CYCLE POWER PLANTS

Nov 7, 2018

| Reference: 

B74077

  • Gas and steam power plant are enabled to take part in the electricity spot market
  • Reduced cost by reduced fatigue damage by up to 90%
  • Retro fit possible
Read more

SCHWEISSVERFAHREN FÜR UNTERSCHIEDLICHE MATERIALKOMBINATIONEN

Nov 7, 2018

| Reference: 

B70287

  • Unterschiedliche Materialkombinationen können verbunden werden
  • Auch schwer schweißbare Werkstoffe können verarbeitet werden
  • Keine Erwärmung auf Schmelztemperatur notwendig
Read more

A CALCIUM-SENSOR FOR NMR/MRI BASED DIAGNOSTIC IMAGING USING HYPERPOLARIZED XENON

Nov 7, 2018

| Reference: 

B75123

  • in vitro, in vivo and ex vivo detection of calcium changes via NMR and MRI & Hyper-CEST
  • in particular for diagnosing and/or monitoring treatment of diseases
Read more

PH-BIOSENSORS BASED ON HYPERPOLARIZED ZYMONIC ACID FOR NONINVASIVE IMAGING AND SPECTROSCOPY

Oct 30, 2018

| Reference: 

B73167

  • Reliable and non-invasive extracellular imaging sensor to localize and quantify pH
  • Potential for diagnosis and therapy of diseases characterized by aberrant acid-base balances
Read more

3D-PRINTING WITH STAMPS OR CONSTRUCTION BRICKS

Oct 17, 2018

| Reference: 

B73089

  • 3D printing
  • Material and time saving process
  • Rapid Prototyping
Read more

SELECTIVE PROTEIN KINASE INHIBITORS TARGETING EPHA2

Oct 17, 2018

| Reference: 

B76157

  • novel EphA2 kinase inhibitors that borrow the chemical scaffold of the drug Dasatinib
  • higher selectivity compared to the existing non-designated alternatives l
  • less likely to be accompanied by side effects arising from off-target inhibition
Read more

AMYLOID INHIBITORY PEPTIDES FOR ALZHEIMER`S DISEASE AND DIABETES

Oct 17, 2018

| Reference: 

B78094

  • macrocyclic peptides (MCIPs): novel class of nanomolar amyloid inhibitors of both Aβ40(42) and IAPP or of Aβ40(42) alone
  • candidates/leads for macrocyclic peptide‐based anti‐amyloid drugs
  • scaffolds for the design of small‐molecule peptidomimetics for targeting amyloidogenesis
Read more

GUIDE VANE FOR AN AXIAL KAPLAN TURBINE

Oct 17, 2018

| Reference: 

B77046

  • Reduced exit swirl downstream of the runner and efficiency improvement                                              
  • Reduction of the dimensions and costs of the turbine                                                                                  
  • Easy synchronization with the turbine generator in the start-up phase
Read more

ADAPTIVE SUCTION HOOD SYSTEM

Oct 17, 2018

| Reference: 

B74143

  • Distance reduction between collecting element and machine                                                                                
  • Increased performance                                                            
  • High versatility
Read more

IMMUNOTHERAPY FOR CHRONIC LIVER DISEASES

Sep 3, 2018

| Reference: 

B72272

  • Novel vaccination strategy against chronic liver diseases through stimulation of IMATEs with TLR9-L
  • IMATEs are an anatomic compartment within the liver tissue consisting of myeloid cells
  • iMATEs overcome regulatory cues that limit immune response during chronic liver infections
Read more

METHOD FOR THE DETERMINATION OF SATELLITE CORRECTION FOR PRECISEPOINT- POSITIONING

Sep 3, 2018

| Reference: 

B77131

  • Fast convergence of satellite corrections                      
  • Possibility of choosing the type of precessing                
  • Mutiple-frequency measurements

Read more

A CONVERTIBLE MULTI-PURPOSE BIOREACTOR

May 4, 2018

| Reference: 

B76089

  • ‍Convertible multi-purpose bioreactor provides 4in1 combination of different types of bioreactosr:
  • stirred-tank bioreactor
  • gas-lift bioreactor
  • packed-bed biofilm reactor
  • trickling filter biofilm reactor
Read more

ANTIGENIC PEPTIDES FOR THE DIAGNOSIS, THERAPY-MONITORING AND TREATMENT OF PSORIASIS

May 4, 2018

| Reference: 

B75034

  • ‍Diagnosis of psoriasis (monitoring disease acitivity / efficacy of treatment / defining disease risk)
  • Treatment of psoriasis (Using altered peptide ligands / using toxin-coupled toxins / blocking HLA-C/T-cell-interactions)
Read more

PROCESS FOR THE PRODUCTION OF ALCOHOLS

Apr 16, 2018

| Reference: 

B77074

  • Synthesis gas (e.g. CO, CO2, H2) is converted by microorganisms in a bioreactor 
  • cascade of two serially connected stirred-tank reactors 
  • Utilization for small application as well as for industrial scale up
Read more

CHEMICAL DISRUPTION OF CLPX INHIBITS MULTIRESISTANT S. AUREUS

May 4, 2018

| Reference: 

B76071

  • In vitro & in vivo proof of concept
  • Novel compounds for the inhibiton of bacterial virulence
  • Available as mono therapy or as combination therapy with antibiotics
Read more

SPECIFIC IMAGING AGENTS FOR PRIMARY ALDOSTERONISM DIAGNOSTICS

Mar 23, 2018

| Reference: 

B76123

  • non-invasive differentiation between bilateral hyperplasia and unilateral adenoma by PET-imaging
  • radiolabeled aldosterone synthase (CYP11B2) inhibitors with high selectively, easy synthesis and high chemical and metabolic stability
  • alternative for the so far performed invasive diagnostic adrenal vein sampling in combination with cross-sectional imaging
Read more

SUCCESS PREDICTION OF AN ALLERGEN SPECIFIC IMMUNOTHERAPY

Mar 23, 2018

| Reference: 

B76137

  • Innovative prediction method for the therapeutic success of an allergen-specific immunotherapy (AIT) at an early stage
  • straightforward and easy determination of the relevant parameters from nasal sample material
  • patient-friendly and economic
Read more

ROBUST WIFI-BASED INDOOR LOCALIZATION

Mar 19, 2018

| Reference: 

B77076

  • Navigation through a building with the aid of a smatphone app
  • Highly precise localization (below 1m)
  • Robustness to environmental changes
Read more

COMPACT UNIT FOR COST-EFFICIENT PUNCH VELOCITY CONTROL

Mar 19, 2018

| Reference: 

B76058

  • Velocity modulation with respect to the upper stage tool velocity
  • Simulataneous operation
  • Quality improvement of the workpiece
Read more

STORAGE AND RELEASE OF WHITE PHOSPHORUS AND YELLOW ARSENIC

Jan 15, 2018

| Reference: 

B76034

  • White Phosphorus (P4) and Yellow Arsenic (As4) are of great interest for syntheses and other industrial applications
  • The handling of P4 and As4 is very complex due to the high reactivity, the metastability and toxicity
  • A facile storage and release method for P4 and As4, respectively, is now available
Read more

MOBILIZING BROWN FAT THERMOGENESIS

Nov 25, 2017

| Reference: 

B75239

  • Endogenously occuring natural peptide
  • Non-adrenergic activator
  • Increasing negative energy
Read more

QUICK SIMULATION OF THE LOAD ON A DISTRIBUTION GRID

Nov 27, 2017

| Reference: 

B75231

  • Electrical distribution grid simulation
  • Extremely small conputational time
  • Versatile implementation (small and big distribution grids)
Read more

HYDROXYINDALPINE DERIVATIVES FOR THE TREATMENT OF GI DISORDERS

Nov 14, 2017

| Reference: 

B72118

  • Serotonin receptor agonist
  • Highly specific
  • Extremely stable against hydrolysis and oxidation
Read more

DETECTION AND TRACKING OF OBJECTS IN WATER USING A NOVEL SONAR TECHNIQUE

Nov 14, 2017

| Reference: 

B75144

  • High temporal resolution
  • Measurement of the change of acustic impedence and frequency
  • Identifying and trascking of single individuals (water animals)
Read more

PROCESS FOR EXTRACTION OF ANTIOXIDANTS FROM PLANT MATERIAL

Nov 13, 2017

| Reference: 

B76039

  • New green extraction method
  • Selective extraction of carnosic acid with a non-flammable, non-toxic and green aqueous micellar solution
  • Can be used as flavours, antioxidants and oil-soluble preservatives
Read more

PACKING SOLUTION FOR FIXING POT PLANTS AND OTHER SENSITIVE PRODUCTS

Nov 13, 2017

| Reference: 

B76191

  • Safe transportation of sensitive goods
  • Cost effective
  • Less package material
Read more

IMPROVING ELECTRON BEAM MELTING

Nov 13, 2017

| Reference: 

B76154

  • Higher resolution
  • Faster build up process
  • More energy efficient
Read more

LOCAL IMMUNE CHECKPOINT INHIBITION

Nov 13, 2017

| Reference: 

B75080

  • Trispecific molecules (LiCADs, local inhibitor checkpoint antibody derivatives) enable local (tumor) immune checkpoint inhibition, which avoids systemic side effects
  • LiCADs comprise binding sites with specificity for a tumor cell, for an effector cell and for a checkpoint molecule
  • Checkpoint binding is restricted and concentrated to tumor cells avoiding undesired toxicity to healthy cells and accordingly systemic side effects
Read more

HYDROPHOBIC MORTAR

Nov 13, 2017

| Reference: 

B75015

  • Mortar hybrid material with superior characteristics: strong hydrophobic properties, no need for post-treatment, not harmful to the environment
  • Supplementation of a bacterial biofilm leads to an increased roughness on the microscale and the nanoscale, and on both the outer and inner surface, imitating the lotus effect
  • Lyophilized powder of the bacterial biofilm available as dry admixture
Read more

MODULAR MULTILEVEL BATTERY

Nov 13, 2017

| Reference: 

B73264

  • A new Modular Multilevel Converter (MMC) with parallel connectivity
  • Intelligent battery systems for electromobility of tomorrow
  • Nearly loss free balancing of cells
Read more

CAPACITIVE FORCE SENSOR AND FABRICATION METHOD

Nov 13, 2017

| Reference: 

B72026

  • Interactive Robot Skin
  • Intuitive Interaction with Robots
  • Save Human/Robot Collaboration
Read more

NF-κB-ACTIVATED DENDRITIC CELLS

Nov 13, 2017

| Reference: 

B71259

  • Novel DC-vaccination strategy for cancer immunotherapy that has very little adverse effects and overcomes the limitations of DC based immunotherapy approaches
  • DCs activation is mediated by triggering their NF-κB-pathway via mRNA transfection
  • Activated DCs show increased IL-12 production, have the capacity to repetitively stimulate and expand antigen-specific CTLs, lead to strong expansion of effector T cells (memory T cells) and are much more stable compared to other DC vaccination products
Read more

URINARY MARKER FOR BLADDER CANCER DETECTION

Nov 13, 2017

| Reference: 

B71211

  • The focal adhesion protein LASP-1 is a novel and simply detectable marker for urothelial carcinoma of the bladder (UCB)
  • LASP-1 overcomes the limitation of currently used cystoscopy and urine cytology for diagnosis of UCB
  • LASP-1 is detected in voided urine sediment of bladder cancer patients and is combinable with a second marker to further raise specificity/sensitivity
Read more

ROBUST GRAPHENE-CONTACTS FOR SiC

Nov 13, 2017

| Reference: 

B71049

  • High power switch
  • Graphene contacts
  • Normally Off SiC transistor
Read more

PRODUCTION PROCESS FOR PRINTED CIRCUIT BOARDS

Nov 13, 2017

| Reference: 

B70311

  • Economical processing
  • Fast friction coating
  • Flexible materials
Read more

CLASS A SURFACES FOR CARBON COMPOSITE COMPONENTS

Nov 13, 2017

| Reference: 

B70124

  • Carbon composite surfaces
  • Class A surfaces
  • Process automation and cost reduction
Read more

DETECTION OF IMPURITIES IN THE SUB-PPB RANGE

Sep 17, 2018

| Reference: 

B69177

  • Detection for  impurities in sub-ppb range in liquid phase                                                                          
  • Continuous flow measurement
  • Spectroscopic approach for metallics impurities and emtallic complexes
Read more

TUNABLE LIGHTSOURCE WITH CASCADING PHASE-SHIFTING FILTERING

Nov 13, 2017

| Reference: 

B68023

  • A sweeping light source for MHz-OCT (optical coherence tomography)
  • Tunable light sources down to 600 nm
  • 340 000 sewps per second, 0.1 nm linewidth.
Read more

LIGHT SENSOR (MIR-VIS) - HIGHLY SENSITIVE AT ROOM TEMPERATURE

Nov 13, 2017

| Reference: 

B67342

  • Detector design based on resonance tunneling diode (RTD)
  • Detection range 400-4000nm
  • High sensitivity and high speed.
Read more

TUNABLE FDML LASER

Oct 17, 2018

| Reference: 

B67035

  • A sweeping light source for MHz-OCT (optical coherence tomography)
  • Medicine, e.g. Ophthalmology, Skin Cancer Diagnosis
  • Material Sciences
Read more

PROCESS FOR ISOLATION OF ODORIFEROUS AGENTS

Oct 27, 2017

| Reference: 

B75122

  • Gentle method for isolation of odoriferous agents
  • Almost complete extraction 
  • Extraction within a short time and moderate temperatures
Read more

HIGHLY ACTIVE AND SELECTIVE LIGANDS FOR INTEGRIN avß6

Oct 27, 2017

| Reference: 

B75165

  • Highly upregulated avß6 in different types of cancer
  • Peptides with remarkable affinity and high selctivity
  • No binding affinity toward other RGD-recognizing integrins
Read more

VSV/NDV HYBRID VIRUS CANCER THERAPY

Sep 3, 2018

| Reference: 

B75267

  • ‍VSV/NDV hybrid enables efficient tumor cell killing.
  • VSV/NDV hybrid virus effectively overcomes the safety concerns of each parental virus and
  • combines the advantages of both vesicular stomatitis virus (VSV) and Newcastle disease virus (NDV) vectors
Read more

HYDROGELS: INJECTABLE DEPOT-SYSTEMS

Sep 18, 2018

| Reference: 

B76151

  • that gelatinize by a dual mechanism based on Diels-Alder reaction and physical crosslinking
  • Stability and stiffness can be adjusted to therapeutic need
  • Hydrogels are stable, in situ forming, non-toxic and particularly suitable for controlled drug release
Read more

PROTEIN PURIFICATION/IMMOBILIZATION THROUGH NEG-PEPS

Sep 16, 2017

| Reference: 

B76080

  • NegPeps (magnetic particle binding peptides) are novel peptides with the potential to replace the common affinity tags based protein purification/immobilization 
  • NegPeps bind to magnetic nanoparticles in a reversible and controlled manner
  • No specific surface functionalization necessary 
Read more

COMPRESSED AIR STORAGE FOR INDUSTRIAL APPLICATIONS

Sep 16, 2017

| Reference: 

B76054

  • ‍Energy and money savings 
  • Efficient gas storage (e.g. hydrogen) Improved availability
Read more

CONCEPT FOR HERMETIC, LOW HEAT, MINIMUM INDUCTION PACKAGING FOR SEMICONDUCTOR CHIPS

Oct 17, 2018

| Reference: 

B76018

  • Efficient protection from the atmosphere
  • Thermal resistance reduction
  • Induction and parasitics effects reduction.
Read more

MODIFIED BNC FOR CHIP CARDS AND MEDICINE

Sep 3, 2018

| Reference: 

B76007

  • Novel chip technology that can be used as a data storage system, as a computer chip or a wearable
  • Principle: modification of bacterial nanocellulose (BNC) with light-gated DNA-Polymerases and other components 
  • Enables information read in and read out by using DNA, Polymerases and Exonucleases
Read more

NEW PROCESS FOR HIGH PERFORMANCE POLYMERS

Sep 16, 2017

| Reference: 

B75246

  • Synthesis of known polymers to be simpler and more cost-effective 
  • Conversion of monomers which until now have not yet been polymerized by conventional methods 
  • Highly active catalyst
Read more

RAPID FOCUS DETERMINATION DURING LASER BEAM WELDING

Sep 16, 2017

| Reference: 

B75226

  • ‍Rapid focus determination 
  • Upgradeable Easy calibration of scanner optics
Read more

INTERACTIVE ROBOT SURFACE

Sep 16, 2017

| Reference: 

B75182

  • ‍Intuitive Human Robot Interaction 
  • Context-based communication 
  • Robot-robot recognition
Read more

NEW THERMALLY STABLE EXPLOSIVE

Sep 16, 2017

| Reference: 

B75154

Highlights and advantages of TKX-55 compared to commercially available and widely used explosives, e.g. PYX and HNS:

  • Thermally stable, up to 335 °C
  • High performance, showing high density (1.837 g.cm-3 ) and high velocity of detonation (8030 m.s-1)
  • Yielding detonation pressure over 270 kbar  and low sensitivity
Read more

LIGHT SENSOR FOR FAR INFRARED (4-30 μm)

Sep 16, 2017

| Reference: 

B75131

  • ‍Detector design based on resonance tunneling diode 
  • Range 4-20 μm, high sensitivity, high speed
  • Ideal replacement for toxic HgCdTe-Detectors
Read more

SnIP: A NEW SEMICONDUCTOR

Sep 16, 2017

| Reference: 

B75074

  • ‍Tin phosphor iodide (SnIP) is a new semiconductor material
  • Photoluminescence in the visible makes it interesting for solar cells and light emitting diodes
  • First inorganic double helix structure material
Read more

MONOLITHICALLY INTEGRATED NANOWIRE LASERS ON SILICON

Oct 17, 2018

| Reference: 

B75073

  • Reduction of the production costs for laser diodes                                                                                                
  • Chip-scal optical communication
  • Increased computational speed and reduced energy consuption for digital divices
Read more

CANNULA FOR OCULAR MICRO-INJECTION

Sep 16, 2017

| Reference: 

B75028

  • ‍Intra- and sub-retinal targeted administration of drugs 
  • Easy and highly precise targeting 
  • Treatment of Age-related Macular Degeneration (AMD)
Read more

3D-PRINTING USING FOCUSED SUPER SONIC BEAMS

Sep 16, 2017

| Reference: 

B75001

  • ‍Ultra sonic 3d printing allows manufacturing from the volume
Read more

PROCESSING A FOAM WORK PIECE

Sep 16, 2017

| Reference: 

B74222

  • ‍New product properties 
  • Better processing Flexible processing
Read more

WET-LAID MEETS ELECTROSPINNING

Sep 16, 2017

| Reference: 

B74211

  • Milder to skin compared to sodium dodecyl sulfate (SDS), in combination with a reduced sensitivity to water hardness
  • Low production costs compared to ethoxylated anionic surfactants
  • Enhanced washing ability and solubilizing power due to high water solubility
Read more

NEW DRUG TARGET IN ALZHEIMER DISEASE

Sep 16, 2017

| Reference: 

B74174

  • Aη-α as a new drug target and / or diagnostic marker for Alzheimer disease
  • Presence of Aη-α fragments in AD brains should be taken into account for development/applicati- on of drugs targeting Aβ or inhibiting β-secretase, since these lead to accumulation of Aη-α
  • Antibodies to detect η-secretase pathway peptides are available
Read more

ONE-POT PROCEDURE FOR NCC ISOLATION

Sep 3, 2018

| Reference: 

B74068

  • ‍Conventional Production of NCC is complex, expensive and takes several days
  • Novel simplified method for NCC isolation: neutralization-based isolation
  • Significantly enhanced yield, accelerated process and reduced water usage
Read more

A NEW TARGET IN CANCER THERAPY

Sep 16, 2017

| Reference: 

B74064

  • Cancer cells use an extracellular citrate supply as an important energy source and substrate for the synthesis of critical cellular building blocks (e.g. fatty acids). 
  • A highly specialized plasma membrane protein (pmCiC, plasma membrane citrate carrier) was found to be responsible for citrate uptake in cancer cells
  • pmCiC is a novel and specific marker and therapeutic target for cancer cells
Read more

INDEXING OF HEMODYNAMIC PARAMETERS CONSIDERING THE INDIVIDUAL CONTEXT

Sep 16, 2017

| Reference: 

B74058

  • ‍Better assessment of patient health status and an easily accesible presentation
Read more

METHOD AND DEVICE FOR 2D-SEPARATION OF IONIC SPECIES

Sep 16, 2017

| Reference: 

B74051

  • ‍Efficient separation of bioanalytical samples 
  • High troughput High sensitivity
Read more

HYDRODABCYL: A HYDROPHILIC DARK QUENCHER

Sep 16, 2017

| Reference: 

B74047

  • ‍Hydrodabcyl: A hydrophilic alternative to the commonly used dark quencher Dabcyl
  • Non-immunogenic and non-toxic
  • Perfectly suitable for a large variety of biological and biochemical systems
Read more

METHOD FOR DEMODULATION AND DEMODULATOR

Sep 16, 2017

| Reference: 

B74021

  • ‍Low energy solution for 5G-standard telecommunication
Read more

SMALL MOLECULE HDAC6 INHIBITORS

Sep 16, 2017

| Reference: 

B73271

  • ‍HDAC6 is a promising target for the treatment of chronic immune and inflammatory disorders such as rheumatoid arthritis (RA)
  • Marbostat are new small molecule inhibitors of HDAC6 with superior characteristics: in comparison to the established HDAC6 inhibitor Tubastatin A, the new inhibitors are more potent and specific, and most importantly they highly and selectively inhibit the enzyme activity of HDAC6 without destroying the protein.
  • Provision of a viable alternative to first line NSAIDs (non-steroidal anti-inflammatory drugs) in the treatment of RA
Read more

IMPROVING STABILITY AND SECRETION OF ANTIBODIES

Sep 16, 2017

| Reference: 

B73076

  • Improvement of the biophysical properties of antibodies and enhancement of antibody secretion by imitating the stabilizing structural elements of shark antibodies
  • CL domain is modified by a conservative exchange of amino acids at two positions
  • Compared to the wild type CL, the melting point of the modified CL domain is almost 10°C higher and its stability against urea-induced denaturation is also markedly increased 
Read more

FAST AND EXACT CALCULATION OF THE EFFICIENCY OF COMBUSTION PROCESSES

Sep 16, 2017

| Reference: 

B72156

  • ‍Precise specifications of turbines and engines 
  • Accurate calculation of efficiencies 
  • Guaranteed performance
Read more

NEW SEROTONIN RECEPTOR AGONISTS

Sep 16, 2017

| Reference: 

B72118

  • New serotonin receptor 5HT1P agonists (5-Benzyloxyindalpine, 5 BOIP) for the treatment or prevention of GI diseases such as constipation and functional dyspepsia and, in particular, for relieving GI symptoms
  • In the proximal stomach, 5BOIP evokes muscle relaxation, thereby improving the gastric accommodation reflex
  • 5 BOIP is highly specific, extremely stable against hydrolysis and oxidation and is much more convenient in production than other known agonists
Read more

SMALL MOLECULE INHIBITORS OF CD40-TRAF6 INTERACTIONS

Sep 16, 2017

| Reference: 

B72031

  • New selective inhibitors for treatment of chronic inflammatory diseases, such as atherosclerosis, obesity and multiple sclerosis
  • Inhibitors selectively block CD40-TRAF6 interactions
  • The selective blockage of the CD40-TRAF6 interactions strongly reduces inflammation, whereas unwanted immune-suppressive side effects are reduced
Read more

METHOD FOR IDENTIFICATION OF TARGET ANTIGENS OF T-CELLS

Sep 16, 2017

| Reference: 

B70007

  • Identify peptide (CD4 ongoing)
  • Affinity independent and extremely sensitive method
  • Focused on autoimmune diseases and psoriasis but also applicable to tumor immunology
Read more

CHOLINE COMPOUNDS AND THEIR USE AS SURFACTANTS

Sep 16, 2017

| Reference: 

B69024

  • Milder to skin compared to sodium dodecyl sulfate (SDS), in combination with a reduced sensitivity to water hardness
  • Low production costs compared to ethoxylated anionic surfactants
  • Enhanced washing ability and solubilizing power due to high water solubility
Read more